Aminobenzoic acids and derivatives
Aobchem N N-diethyl-4-methylbenzamide | ≥95% | CAS 2728-05-4 | C12H17NO | 1g
N N-diethyl-4-methylbenzamide | ≥95% | CAS 2728-05-4 | C12H17NO | 1g
Medchemexpress LLC Benzamide, 3-amino | 3544-24-9 | 100.0% | 1 ML
3-Aminobenzamide (PARP-IN-1) is a small-molecule inhibitor of poly(ADP-ribose) polymerase (PARP) used in biochemical and cellular research to probe DNA repair and cell death pathways. It exhibits an IC50 of approximately 50 nM in CHO cells and is supplied as a high-purity reagent suitable for research applications.
- Potent PARP inhibitor with an IC50 of approximately 50 nM in CHO cells.
- High purity: HPLC 99.97%.
- Provided as a concentrated solution (10 mM, 1 mL) or as a solid for flexibility in assays.
- Chemical formula C7H8N2O; molecular weight 136.15 g/mol.
![eMolecules 169869-90-3 | Exatecan mesylate | Ambeed | MFCD04113012 | 531.560 | C25H26FN3O7S | 98.000 | CS(O)(=O)=O.CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](N)c(c3Cn1c2=O)c45 | 1g | 784396078](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000216525.jpg-250.jpg)
eMolecules 169869-90-3 | Exatecan mesylate | Ambeed | MFCD04113012 | 531.560 | C25H26FN3O7S | 98.000 | CS(O)(=O)=O.CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](N)c(c3Cn1c2=O)c45 | 1g | 784396078
Exatecan mesylate | Ambeed | 169869-90-3 | MFCD04113012 | 531.560 | C25H26FN3O7S | 98.000 | CS(O)(=O)=O.CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](N)c(c3Cn1c2=O)c45 | 1g | 784396078
Medchemexpress LLC Cp-506 mesylate | 2227304-19-8 | 98.6% | 681.60 | 5 MG
Cp-506 mesylate is a light yellow to yellow solid. This product has been tested and complies with the given specifications. It is important to note that this product has not been fully validated for medical applications and is intended for research use only.
- Cas number: 2227304-19-8
- Molecular weight: 681.60
- Purity: 98.59%
- Storage conditions for powder: -20°C for 3 years, 4°C for 2 years
- Storage conditions in solvent: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Pritelivir (mesylate hydrate) | 1428321-10-1 | C19H24N4O7S3 | 25 MG
Pritelivir (mesylate hydrate) | 1428321-10-1 | C19H24N4O7S3 | 25 MG
Medchemexpress LLC NSC243928 mesylate | 59988-01-1 | 99.3% | 503.59 g/mol | C23H25N3O6S2 | 10MM 1ML
NSC243928 mesylate is a small-molecule LY6 (lymphocyte antigen 6) binder with reported antiproliferative and anticancer activity. It is available as a solid and as a ready-to-use 10 mM solution in DMSO for cell-based assays; published data report activity against several breast and ovarian cancer cell lines.
- Binds LY6 family proteins and inhibits cell growth.
- Reported IC50s: MDA-MB-231 5.683 μM; Hs-578-T 7.309 μM; BT-549 7.954 μM; OVCAR-8 4.167 μM.
- Available as solid and 10 mM solution in DMSO (1 mL).
- High purity: 99.33%.
- Molecular formula: C23H25N3O6S2; molecular weight: 503.59 g/mol.
- Soluble in DMSO to 10 mg/mL (≈19.86 mM) with warming.
- Store sealed, away from moisture; in solvent: -80°C up to 6 months, -20°C up to 1 month.
Medchemexpress LLC Gabexate (mesylate) | 56974-61-9 | 98.64% | 100 MG
Gabexate mesylate (FOY) is a competitive and non-antigenic synthetic inhibitor of trypsin-like serine proteinases. It inhibits human thrombin, urokinase, plasmin, and Factor Xa, and binds to human and bovine tryptase. It is used for pancreatitis and disseminated intravascular coagulation, and decreases proliferation rate in HepG2 cells in vitro.
- Anticoagulant effect by inhibiting the clotting activity of thrombin.
- Anti-inflammatory effect through the inhibition of NF-κB, proinflammatory cytokines, and nitric oxide.
- Therapeutic applications for pancreatitis and disseminated intravascular coagulation.
- Decreases the proliferation rate of HepG2 cells in a dose-dependent manner.
- Attenuates the development of mechanical allodynia induced by spinal nerve ligation (SNL) and inhibits the expression of pro-inflammatory cytokines after SNL in a rat model.
Medchemexpress LLC Pefloxacin mesylate | 70458-95-6 | 99.7% | 1 G
Pefloxacin mesylate is a broad-spectrum antibiotic that blocks DNA replication by inhibiting DNA gyrase and DNA relaxation catalyzed by topoisomerase I. It exhibits antibacterial activity against various bacteria such as *Escherichia coli*, *Pseudomonas aeruginosa*, and *Bacteroides fragilis*. It has also shown activity against *Plasmodium yoelii* infection and can increase UVA-induced edema and immunosuppression, making it suitable for infection studies.
- Inhibits DNA replication by blocking DNA gyrase
- Inhibits DNA relaxation catalyzed by topoisomerase I (IC50 of 45 μg/mL)
- Exhibits broad-spectrum antibacterial activity
- Active against *Escherichia coli*, *Pseudomonas aeruginosa*, and *Bacteroides fragilis*
- Demonstrates activity against *Plasmodium yoelii* infection
- Increases UVA-induced edema and immunosuppression
- Suitable for infection studies
Medchemexpress LLC AZ7550 mesylate (AZ7550 trimesylate salt) | 2319837-99-3 | 98.7% | 773.90 g·mol⁻¹ | C30H43N7O11S3 | 10 MG
AZ7550 mesylate is the mesylate (trimesylate) salt of AZ7550, an active metabolite of AZD9291 that inhibits IGF1R (IC50 = 1.6 μM). It is provided as an analytical standard for biochemical and cellular research and is offered in small milligram packages and solution formats for assay use.
- Mesylate (trimesylate) salt form for improved handling and solubility.
- Reported IGF1R inhibitory activity with IC50 = 1.6 μM.
- High purity (~98.7%), suitable as an analytical standard.
- Molecular weight 773.90 g·mol⁻¹ and formula C30H43N7O11S3.
- Available in small quantities (5-100 mg) and as DMSO solutions for assay readiness.
Medchemexpress LLC Sns-314 mesylate | 1146618-41-8 | ≥98.0% | 25 MG
SNS-314 mesylate is the mesylate salt of SNS-314, a potent pan-Aurora kinase inhibitor active against Aurora A, B, and C used in preclinical research to investigate mitotic regulation and antineoplastic mechanisms.
- Potent inhibition of Aurora A, B, and C (IC50 ≈ 9, 31, and 6 nM)
- High purity: ≥98%
- Powder form, soluble in DMSO for screening and formulation
- Typical storage: -20 °C to preserve stability
- Provided as mesylate salt; formula C18H15ClN6OS2 • CH3SO3H, formula weight 527.0
Medchemexpress LLC Nafamostat formate salt-13C6 | 98.1% | 1 MG
Nafamostat formate salt-13C6 is a 13C labeled Nafamostat, a synthetic serine protease inhibitor and anticoagulant. It suppresses T cell auto-reactivity by decreasing granzyme activity and CTL cytolysis, and also blocks activation of SARS-CoV-2. This compound is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Features a 13C labeled structure.
- Acts as a synthetic serine protease inhibitor.
- Functions as an anticoagulant.
- Suppresses T cell auto-reactivity.
- Blocks activation of SARS-CoV-2.
AdipoGen Talabostat mesylate
Chemical. CAS 150080-09-4. Formula C9H19BN2O3 . CH4O3S. MW 310.2. Talabostat is an orally bioavailable non-selective inhibitor of dipeptidyl-peptidases DPPs, including DPP-4, DPP-7/QPP, DPP-8, DPP-9, fibroblast activation protein FAP and prolyl endopeptidase PREP PEP IC50s = >4, 310, 4, 11, 560 and 390 nM, respectively. Talabostat induces powerful anti-tumor immune responses in cancer models. Talabostat is a NLRP1 and caspase recruitment domain family member 8 CARD8 inflammasome activator. Talabostat triggers an immunostimulatory form of programmed cell death known as pyroptosis selectively in monocytes and macrophages. DPP8/9 inhibition by Talabostat activates the inflammasome sensor protein Nlrp1b, which in turn activates pro-caspase-1 to mediate pyroptosis, suggesting that DPP8/9 serve as an intracellular checkpoint to restrain Nlrp1b and the innate immune system.
![eMolecules 169869-90-3 | Exatecan mesylate | Ambeed | MFCD04113012 | 531.560 | C25H26FN3O7S | 98.000 | CS(O)(=O)=O.CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](N)c(c3Cn1c2=O)c45 | 100mg | 784396076](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000126098.jpg-250.jpg)
eMolecules 169869-90-3 | Exatecan mesylate | Ambeed | MFCD04113012 | 531.560 | C25H26FN3O7S | 98.000 | CS(O)(=O)=O.CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](N)c(c3Cn1c2=O)c45 | 100mg | 784396076
Exatecan mesylate | Ambeed | 169869-90-3 | MFCD04113012 | 531.560 | C25H26FN3O7S | 98.000 | CS(O)(=O)=O.CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](N)c(c3Cn1c2=O)c45 | 100mg | 784396076
Medchemexpress LLC NSC243928 mesylate | 59988-01-1 | 99.3% | 503.59 g·mol⁻¹ | C23H25N3O6S2 | 5MG
NSC243928 mesylate is the mesylate salt of NSC243928, a small-molecule binder of human lymphocyte antigen 6 (LY6) that inhibits cell growth and exhibits anticancer activity in vitro. Reported activity includes induction of cell death and IC50 values in the low micromolar range against multiple cancer cell lines.
- Solid, light yellow to yellow physical form.
- Purity 99.33%.
- Molecular weight 503.59 g·mol⁻¹ and formula C23H25N3O6S2.
- Soluble in DMSO (10 mg/mL; may require sonication and warming).
- Recommended storage: solid at 4°C; solutions at -80°C (6 months) or -20°C (1 month).
- Provided in small research pack sizes and ready-to-use 10 mM DMSO solutions.
Medchemexpress LLC Encequidar mesylate | 849675-87-2 | 99.6% | 784.83 | 50 MG
Encequidar mesylate is a competitive and potent P-glycoprotein inhibitor. This product is for research use only.
- Target: P-glycoprotein
- Appearance: Solid, light yellow to yellow
- Solubility in DMSO: 25 mg/mL (31.85 mM), requires ultrasonic
- Improved in vivo absorption with microcapsule form
- Involved in clinical trials for metastatic breast cancer, breast neoplasms, and solid tumors